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Pseudo-UTP

lithium (5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl triphosphate （订货以CAS编码或英文名称为准）

A modified nucleoside-5’-O-triphosphate, commonly used for drugable mRNA synthesis
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编号：PC13108
分子式：C9H15N2O15P3(FREEACID)
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货号 品牌 规格 纯度/含量 标准价 优惠价 库存货期 数量 购买
PC13108-10ul (100 mM) Medlife 10ul (100 mM)
≥98%
 ¥431.20 登录后可见
PC13108-50ul (100 mM) Medlife 50ul (100 mM)
≥98%
 ¥1999.20 登录后可见
PC13108-100ul (100 mM) Medlife 100ul (100 mM)
≥98%
 ¥3426.08 登录后可见
英文名称： lithium (5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl triphosphate
分子式： C9H15N2O15P3(FREEACID)
详细描述

Pseudo-UTP, also known as pseudouridine-5’-O-triphosphate, is one of the most commonly used modified nucleoside-5’-O-triphosphates. Pseudo-UTP is a building block for the polymerase-mediated synthesis of RNA molecules. RNA molecules, especially messenger RNAs (mRNAs), have widespread applications in therapeutic and diagnostic areas, and have demonstrated their superiority over plasmid DNA techniques in both gene and vaccination therapy. Compared with uridine-containing unmodified mRNAs, the application of pseudouridine-containing modified mRNAs exhibits better nuclease stability, immunogenicity, and translational properties. Thus, pseudo-UTP could be used to develop drugable mRNAs with improved properties, by replacing the standard bases by modified ones.
性状 Solution
SMILES O=C(NC=C1C2C(O)C(O)C(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O2)NC1=O.[Li+].[Li+].[Li+].[Li+]
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